Products for Research Use Only
RegisterLogin

Doxapram (hydrochloride)

CAT: 0804-HY-129146-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-129146-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Doxapram (hydrochloride) is a ventilatory stimulant. Doxapram (hydrochloride) inhibits TASK Tandem Pore (K2P) potassium channel function. Doxapram (hydrochloride) inhibits TASK-1 and TASK-3 with an EC50 values of 410 and 37 nM, respectively. Doxapram (hydrochloride) inhibits TASK-1/TASK-3 heterodimeric channel function with an EC50 value of 9 μM. Doxapram (hydrochloride) can be studied in research on apnea in preterm infants[1][2].
CAS Number
113-07-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Smiles
O=C1N(CC(C1(C2=CC=CC=C2)C3=CC=CC=C3)CCN4CCOCC4)CC.Cl
Molecular Formula
C24H31ClN2O2
Molecular Weight
414.97
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Cotten JF, et al., The ventilatory stimulant doxapram inhibits TASK tandem pore (K2P) potassium channel function but does not affect minimum alveolar anesthetic concentration. Anesth Analg. 2006 Mar;102 (3) :779-85. |[2]Henderson-Smart D, et al., Doxapram treatment for apnea in preterm infants. Cochrane Database Syst Rev. 2004 Oct 18;2004 (4) :CD000074.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-129146S-01Doxapram-d5 (hydrochloride)
HY-B0551-01Doxapram
HY-B0551S-01Doxapram-d8
HY-169852Doxapram intermediate-1
HY-B0500BAlverine (hydrochloride)
HY-W714513VU0469650 (hydrochloride)
HY-W708286-01α-Pyrrolidinobutiothiophenone (hydrochloride)
HY-W492795Quifenadine (hydrochloride)
HY-W012179-01Phenylpiperazine (hydrochloride)
HY-Z6449-01Phenylephrone (hydrochloride)

Alternative Products

CatalogName
GTR19275135-01Doxapram hydrochloride
T0038-01Doxapram hydrochloride hydrate
MBS3605716-01Doxapram hydrochloride monohydrate
CS-BU-00131Doxapram-d8 Hydrochloride
RM-D240107-01Doxapram Hydrochloride Impurity 7
RM-D240105-01Doxapram Hydrochloride Impurity 5
RM-D240109-01Doxapram Hydrochloride Impurity 9
RM-D240104-01Doxapram Hydrochloride Impurity 4
RM-D240106-01Doxapram Hydrochloride Impurity 6
RM-D240103-01Doxapram Hydrochloride Impurity 3

Popular Products