β-CCM

• Description:

  β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and proconvulsant effects. β-CCM enhances emotional reactivity and reduces vulnerability to interference in spatial working memory tasks. β-CCM can be used for research on anxiety-related disorders[1][2].

• Product Name Alternative:

  Beta-CCM; Ro 22-7497

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H312-H315-H319-H332-H335

• Target:

  GABA Receptor

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Purity:

  98.95

• Smiles:

  O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)OC

• Molecular Formula:

  C13H10N2O2

• Molecular Weight:

  226.23

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Krazem A, et al. Effects of diazepam and beta-CCM on working memory in mice: relationships with emotional reactivity. Pharmacol Biochem Behav. 2001 Feb;68 (2) :235-44. |[2]Chapouthier, G., et al. Comparison between the effects of the benzodiazepine receptor ligands methyl beta-carboline-3-carboxylate and diazepam in two learning situations in mice. Psychobiology 19, 58–63 (1991) .

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [69954-48-9]