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L-657743

CAT: 0804-HY-12712Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12712Size:1 Each
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Description
L-657743 is a highly potent, highly selective, and orally active α2-adrenoceptor antagonist. L-657743 can be used in the research of neurological diseases such as depression[1].
CAS Number
111466-41-2
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C1N(C)[C@]2(CCN1C)CCN3CCC4=C(OC5=CC=CC=C54)[C@]3([H])C2
Molecular Formula
C20H25N3O2
Molecular Weight
339.43
References & Citations
[1]Pettibone DJ, et al. Pharmacological profile of a new potent and specific alpha 2-adrenoceptor antagonist, L-657,743. Naunyn Schmiedebergs Arch Pharmacol. 1987 Aug;336 (2) :169-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
α adrenergic receptor

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