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Desogestrel-13C2, d2-1

CAT: 0804-HY-12516S2Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12516S2Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Desogestrel-13C2, d2-1 (Org-2969-13C2, d2-1) is the deuterium labeled and 13C-labeled Desogestrel. Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1][2][3][4].
Product Name Alternative
Org-2969-13C2, d2-1
UNSPSC
12352211
Target
Isotope-Labeled Compounds; Progesterone Receptor
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Others
Smiles
[H][C@@]12C(CC[C@]([H])([C@@]23[H])[C@@]([H])([C@@]4(CC3=C)CC)CC([2H])([C@@]4(O)[13C]#[13CH])[2H])=CCCC1
Molecular Formula
C20 13C2H28D2O
Molecular Weight
314.47
References & Citations
[1]Rosenberg MJ, et al. The effect of desogestrel, gestodene, and other factors on spotting and bleeding. Contraception. 1996 Feb;53 (2) :85-90.|[2]Barkfeldt J, et al. The effects of two progestogen-only pills containing either desogestrel (75 microg/day) or levonorgestrel (30 microg/day) on lipid metabolism. Contraception. 2001 Nov;64 (5) :295-9.|[3]Grandi G, et al. Pharmacokinetic evaluation of desogestrel as a female contraceptive. Expert Opin Drug Metab Toxicol. 2014 Jan;10 (1) :1-10.|[4]Cardani S, et al., Desogestrel down-regulates PHOX2B and its target genes in progesterone responsive neuroblastoma cells. Exp Cell Res. 2018 Sep 15;370 (2) :671-679.|[5]Xie H, et al., Effect of progestin on thyroid function in female Wistar rats. Front Endocrinol (Lausanne) . 2024 Jun 5;15:1362774.|[6]Gassen DT, et al. Evaluation of hormonal suppression with two contraceptive regimens using ethinyl estradiol and desogestrel. Arch Gynecol Obstet. 2013 Feb;287 (2) :289-94.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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