J-104123

• Description:

  J-104123 is an inhibitor of squalene synthase with monocarboxylic acid structure. J-104123 can lower serum cholesterol level in dog models[1].

• UNSPSC:

  12352005

• Target:

  Farnesyl Transferase

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C(C[C@@H](CC(N[C@@H](C)[C@H](/C=C/C1=CC=C2C=CC=CC2=C1)CC3=CC=C(C(Cl)=C3)Cl)=O)C)O

• Molecular Formula:

  C28H29Cl2NO3

• Molecular Weight:

  498.44

• References & Citations:

  [1]Yoshikazu Iwasawa, et al (1996) . J-104,123, a novel and orally-active inhibitor of squalene synthase: Stereoselective synthesis and cholesterol lowering effects in dogs. Bioorganic & Medicinal Chemistry Letters 6 (4) 463-466.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [162037-54-9]