Bay-02752

• Description :

  Bay-02752 (Bay o 2752) is a lipid-lowering agent. Bay-02752 inhibits acyl-CoA activity in liver microsomes (IC50 = 0.95 μg/mL) . Bay-02752 inhibits intestinal cholesterol absorption in rats. Bay-02752 inhibits gallstone formation in hamsters[1][2].

• Product Name Alternative :

  Bay o 2752

• UNSPSC :

  12352005

• Target :

  Acyltransferase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C(N1C(C)CC2=C1C=CC=C2)NCCCCCCCCCCCNC(N3C(C)CC4=C3C=CC=C4)=O

• Molecular Formula :

  C31H44N4O2

• Molecular Weight :

  504.71

• References & Citations :

  [1]AKritchevsky D, et al. Influence of N, N'- (1,11-undecandiyl) bis (2,3-dihydro-2-methyl-1H-indole-1-carboxamide) (BAY 02752) on gallstone formation and regression in hamsters. Pharmacol Res Commun. 1987 Oct;19 (10) :679-84.|[2]Harnett KM, et al.. Effects of Bay o 2752, a hypocholesterolemic agent, on intestinal taurocholate absorption and cholesterol esterification. J Pharmacol Exp Ther. 1989 Nov;251 (2) :502-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [78991-74-9]