PF 1022A (Standard)

• Description:

  PF 1022A (Standard) is the analytical standard of PF 1022A. This product is intended for research and analytical applications. PF 1022A is a cyclooctadepsipeptide with broadspectrum anthelmintic properties produced by fermentation of the fungus Mycelia sterilia. PF 1022A is a channel-forming ionophore. PF 1022A showes strong anthelmintic activities against Ascaridia galli in chickens. PF 1022A also can be used for angiostrongyliasis research[1][2][3].

• UNSPSC:

  12352005

• Target:

  Parasite; Reference Standards

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Infection

• Smiles:

  O=C (N ([C@H] (C (O[C@] (C (N ([C@H] (C (O[C@H] (CC1=CC=CC=C1) C2=O) =O) CC (C) C) C) =O) ([H]) C) =O) CC (C) C) C) [C@H] (OC ([C@@H] (N (C ([C@H] (OC ([C@] (N2C) ([H]) CC (C) C) =O) C) =O) C) CC (C) C) =O) CC3=CC=CC=C3

• Molecular Formula:

  C52H76N4O12

• Molecular Weight:

  949.18

• References & Citations:

  [1]Sasaki T, et al. A new anthelmintic cyclodepsipeptide, PF1022A. J Antibiot (Tokyo) . 1992 May;45 (5) :692-7.|[2]Dornetshuber R, et al. Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Biochem Pharmacol. 2009 Apr 15;77 (8) :1437-44.|[3]Nwosu U, et al. Efficacy of the cyclooctadepsipeptide PF1022A against Heligmosomoides bakeri in vitro and in vivo. Parasitology. 2011 Aug;138 (9) :1193-201.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  133413-70-4