Bempedoic acid (Standard)

• Description :

  Bempedoic acid (Standard) is the analytical standard of Bempedoic acid. This product is intended for research and analytical applications. Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor[1]. Bempedoic acid (ETC-1002) activates AMPK[2].

• Product Name Alternative :

  ETC-1002 (Standard) ; ESP-55016 (Standard)

• UNSPSC :

  12352211

• Target :

  AMPK; ATP Citrate Lyase; Reference Standards

• Related Pathways :

  Epigenetics; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR

• Field of Research :

  Metabolic Disease

• Smiles :

  O=C(O)C(C)(C)CCCCCC(O)CCCCCC(C)(C)C(O)=O

• Molecular Formula :

  C19H36O5

• Molecular Weight :

  344.49

• References & Citations :

  [1]Pinkosky SL, et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54 (1) :134-51.|[2]Filippov S, et al. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug;54 (8) :2095-108.|[3]Pinkosky SL, et al. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013 Jan;54 (1) :134-51.|[4]Filippov S, et al. ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK. J Lipid Res. 2013 Aug;54 (8) :2095-108.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [738606-46-7]