PH-46A

• Description :

  PH-46A is an indane dimer with anti-inflammatory activity. PH-46A can reduced histological damage and serum amyloid A (SAA) levels in colitis mice[1].

• UNSPSC :

  12352005

• Target :

  Others

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C(O)C1=CC=C(C[C@]2(C(C3)=CC4=C3C=CC=C4)[C@H](O)C5=C(C=CC=C5)C2)C=C1.O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)CNC

• Molecular Formula :

  C33H39NO8

• Molecular Weight :

  577.66

• References & Citations :

  [1]Frankish N, et al. 6- (methylamino) hexane-1,2,3,4,5-pentanol 4- (((1S,2S) -1-hydroxy-2,3-dihydro-1H,1'H-[2,2-biinden]-2-yl) methyl) benzoate (PH46A) : a novel small molecule with efficacy in murine models of colitis. J Med Chem. 2012 Jun 14;55 (11) :5497-505.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1380445-04-4]