PPOH (Standard)

• Description:

  PPOH (Standard) is the analytical standard of PPOH. This product is intended for research and analytical applications. PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC50 values of 22 μM and 6.5 μM, respectively[1]. PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC:

  12352100

• Target:

  COX; Cytochrome P450; Reference Standards

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; Others

• Field of Research:

  Others

• Smiles:

  C#CCOC1=CC=CC=C1CCCCCC(O)=O

• Molecular Formula:

  C15H18O3

• Molecular Weight:

  246.30

• References & Citations:

  [1]Melissa A VanAlstine, et al. Effects of acetylenic epoxygenase inhibitors on recombinant cytochrome p450s. Drug Metab Dispos. 2011 Jul;39 (7) :1221-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [206052-01-9]