GSK2181236A

CAT: 0804-HY-119081Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-119081Size:1 Each

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Description

GSK2181236A is a NO-insensitive soluble guanylate cyclase (sGC) activator. GSK2181236A can dilate blood vessels, decrease mean arterial pressure and attenuate the development of cardiac hypertrophy. GSK2181236A can be used for the research of cardiovascular disease, such as hypertension[1].

CAS Number

1160426-89-0

UNSPSC

12352005

Target

Guanylate Cyclase

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=C(C(F)(F)F)N(C2=NC(C3=CC=CC=C3OCC4=CC=C(C5=CC=C(OC(F)(F)F)C=C5)C=C4C)=CC=C2)N=C1)O

Molecular Formula

C31H21F6N3O4

Molecular Weight

613.51

References & Citations

[1]Costell MH, et al. Comparison of soluble guanylate cyclase stimulators and activators in models of cardiovascular disease associated with oxidative stress. Front Pharmacol. 2012 Jul 5;3:128

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

GSK2181236A

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