PhIP-d3

• Description :

  PhIP-d3 (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3) is the deuterium labeled PhIP (HY-118716) . PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is the most abundant of generation of heterocyclic amines (HCA), resulted in the cooking of meat[1][2]. DNA damaging and mutagenic activities. PhIP also has oestrogenic activity that could contribute to its tissue specific carcinogenicity[2].

• Product Name Alternative :

  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-d3

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  [2H]C([2H])([2H])N1C(N)=NC2=NC=C(C=C21)C3=CC=CC=C3

• Molecular Formula :

  C13H9D3N4

• Molecular Weight :

  227.28

• References & Citations :

  [1]Bellamri M, et al. Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate. Toxicol Sci. 2018 Jun 1;163 (2) :543-556.|[2]Papaioannou MD, et ak. The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) elicits estrogenic-like microRNA responses in breast cancer cells. Toxicol Lett. 2014 Aug 17;229 (1) :9-16.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [210049-13-1]