Y 25510

• Description:

  Y 25510 is a 1H-pyrazolo[3,4-b]pyridine-1-acetic acid derivative. Y 25510 stimulates production of cytokines (IL-1α, IL-1β, IL-10 and IL-6) [1][2].

• UNSPSC:

  12352005

• Target:

  Drug Derivative; Interleukin Related

• Related Pathways:

  Immunology/Inflammation; Others

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C(O)CN1N=C(C2=CC=C(OC(C)CN(C)C)C=C2)C3=CC=CN=C31

• Molecular Formula:

  C19H22N4O3

• Molecular Weight:

  354.40

• References & Citations:

  [1]Kusuhara H, et al. (+/-) -3-[4- (2-dimethylamino-1-methylethoxy) -phenyl]-1H-pyrazolo[3,4- B]pyridine-1-acetic acid (Y-25510) stimulates production of IL-1 beta and IL-6 at the level of messenger RNA expression in cultured human monocytes. Int J Immunopharmacol. 1996 Dec;18 (12) :719-28. |[2]Hisadome M, et al. Enhancement of in vivo production of IL-1α and IL-6 in mice by Y-25510, a 1H-pyrazolo [3, 4-b] pyridine-1-acetic acid derivative. International journal of immunopharmacology, 1996, 18 (6-7) : 379-384.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  IL-1; IL-10; IL-6

• CAS Number:

  [145194-32-7]