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Y 25510

CAT: 0804-HY-117461Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117461Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Y 25510 is a 1H-pyrazolo[3,4-b]pyridine-1-acetic acid derivative. Y 25510 stimulates production of cytokines (IL-1α, IL-1β, IL-10 and IL-6) [1][2].
CAS Number
145194-32-7
UNSPSC
12352005
Target
Drug Derivative; Interleukin Related
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(O)CN1N=C(C2=CC=C(OC(C)CN(C)C)C=C2)C3=CC=CN=C31
Molecular Formula
C19H22N4O3
Molecular Weight
354.40
References & Citations
[1]Kusuhara H, et al. (+/-) -3-[4- (2-dimethylamino-1-methylethoxy) -phenyl]-1H-pyrazolo[3,4- B]pyridine-1-acetic acid (Y-25510) stimulates production of IL-1 beta and IL-6 at the level of messenger RNA expression in cultured human monocytes. Int J Immunopharmacol. 1996 Dec;18 (12) :719-28. |[2]Hisadome M, et al. Enhancement of in vivo production of IL-1α and IL-6 in mice by Y-25510, a 1H-pyrazolo [3, 4-b] pyridine-1-acetic acid derivative. International journal of immunopharmacology, 1996, 18 (6-7) : 379-384.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-1; IL-10; IL-6