FR-181074

• Description :

  FR-181074 is a selective and orally active PDE V inhibitor. FR-181074 can specifically block PDE V to inhibit the degradation of cyclic guanosine monophosphate (cGMP) in order to relax smooth muscle. FR-181074 can be used for the researches of cardiovascular disease and endocrinology, such as hypertension and erectile dysfunction[1].

• CAS Number :

  [184147-65-7]

• UNSPSC :

  12352005

• Target :

  Phosphodiesterase (PDE)

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cardiovascular Disease; Metabolic Disease

• Smiles :

  O=C(C1=CC(N(CC2=C(Cl)C=CC=C2)C(CCC)=C3C(C(C)C)=O)=C3C=C1)N

• Molecular Formula :

  C23H25ClN2O2

• Molecular Weight :

  396.91

• References & Citations :

  [1]Jinal PANDYA, et al. Liquid oral formulations for pde v inhibitors. WO 2019/130052 Al. 2019-07-04

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PDE5