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FR-181074

CAT: 0804-HY-117390Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117390Size:1 Each
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Description
FR-181074 is a selective and orally active PDE V inhibitor. FR-181074 can specifically block PDE V to inhibit the degradation of cyclic guanosine monophosphate (cGMP) in order to relax smooth muscle. FR-181074 can be used for the researches of cardiovascular disease and endocrinology, such as hypertension and erectile dysfunction[1].
CAS Number
184147-65-7
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cardiovascular Disease; Metabolic Disease
Smiles
O=C(C1=CC(N(CC2=C(Cl)C=CC=C2)C(CCC)=C3C(C(C)C)=O)=C3C=C1)N
Molecular Formula
C23H25ClN2O2
Molecular Weight
396.91
References & Citations
[1]Jinal PANDYA, et al. Liquid oral formulations for pde v inhibitors. WO 2019/130052 Al. 2019-07-04
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE5

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