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Estrone acetate

CAT: 0804-HY-111182-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0804-HY-111182-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Estrone acetate (Hogival) is an estrogen derivative and an estrogen receptor (ER) activator. It promotes mammary gland development, stimulates pituitary prolactin secretion, and induces the proliferation and activation of lactotrophs (e.g., by reducing prolactin storage granule size while increasing rough endoplasmic reticulum and Golgi apparatus volume density) . Estrone acetate holds potential for endocrine research, particularly in studying estrogen's effects on pituitary function, prolactin regulation, and mammary tumor models[1].
CAS Number
[901-93-9]
Product Name Alternative
Hogival; Oestrone-3-acetate; Puboestrene
UNSPSC
12352005
Hazard Statement
H301-H311-H315-H319-H331-H335-H351
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Smiles
C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OC(C)=O)=C4)[C@@]3([H])CC1)C2=O
Molecular Formula
C20H24O3
Molecular Weight
312.40
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501
References & Citations
[1]McComb DJ, et al. Enhanced responsiveness of lactotrophs in ectopic pituitaries to bromocryptine and estrone acetate. Acta Anat (Basel) . 1981;110 (2) :113-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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