Estrone acetate

• Description :

  Estrone acetate (Hogival) is an estrogen derivative and an estrogen receptor (ER) activator. It promotes mammary gland development, stimulates pituitary prolactin secretion, and induces the proliferation and activation of lactotrophs (e.g., by reducing prolactin storage granule size while increasing rough endoplasmic reticulum and Golgi apparatus volume density) . Estrone acetate holds potential for endocrine research, particularly in studying estrogen's effects on pituitary function, prolactin regulation, and mammary tumor models[1].

• Product Name Alternative :

  Hogival; Oestrone-3-acetate; Puboestrene

• UNSPSC :

  12352005

• Hazard Statement :

  H301-H311-H315-H319-H331-H335-H351

• Target :

  Estrogen Receptor/ERR

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Smiles :

  C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(OC(C)=O)=C4)[C@@]3([H])CC1)C2=O

• Molecular Formula :

  C20H24O3

• Molecular Weight :

  312.40

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]McComb DJ, et al. Enhanced responsiveness of lactotrophs in ectopic pituitaries to bromocryptine and estrone acetate. Acta Anat (Basel) . 1981;110 (2) :113-20.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [901-93-9]