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Docosatetraenylethanolamide

CAT: 0804-HY-110016-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-110016-01Size:5 mg
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Description
Docosatetraenylethanolamide (DEA) is a cannabinoid receptor 1 (CB1) agonist. Docosatetraenylethanolamide inhibits the specific binding of cannabinoid probe to rat synaptosomal membranes with a Ki value of 34.4 nM. Docosatetraenylethanolamide can be used in the research of nervous system[1][2].
CAS Number
150314-35-5
Product Name Alternative
DEA
UNSPSC
12352211
Hazard Statement
H225-H350
Target
Cannabinoid Receptor; Endogenous Metabolite
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(NCCO)=O
Molecular Formula
C24H41NO2
Molecular Weight
375.59
Precautions
P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P405-P501
References & Citations
[1]Hanus L, et al. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J Med Chem. 1993 Oct 1;36 (20) :3032-4.|[2]Pertwee R, et alcts of two endogenous fatty acid ethanolamides on mouse vasa deferentia. Eur J Pharmacol. 1994 Jul 1;259 (2) :115-20.|[3]Walter L, et al. Astrocytes in culture produce anandamide and other acylethanolamides. J Biol Chem. 2002 Jun 7;277 (23) :20869-76.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CB1