Cedazuridine (Standard)

• Description :

  Cedazuridine (Standard) is the analytical standard of Cedazuridine. This product is intended for research and analytical applications. Cedazuridine (E7727) (Compound 7a) is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine can be used for cancer research[1].

• CAS Number :

  [1141397-80-9]

• UNSPSC :

  12352100

• Target :

  Others; Reference Standards

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  O[C@H]1C(F)(F)[C@H](N(CC[C@@H](O)N2)C2=O)O[C@@H]1CO

• Molecular Formula :

  C9H14F2N2O5

• Molecular Weight :

  268.21

• References & Citations :

  [1]Ferraris D, et al. Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. J Med Chem. 2014 Mar 27; 57 (6) :2582-8.|[2]Ramsey H E, et al. Oral azacitidine and cedazuridine approximate parenteral azacitidine efficacy in murine model. Targeted Oncology, 2020, 15 (2) : 231-240.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards