Crisnatol (Standard)

• Description :

  Crisnatol (Standard) is the analytical standard of Crisnatol. This product is intended for research and analytical applications. Crisnatol (BWA770U) is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts[1][2][3].

• CAS Number :

  [96389-68-3]

• UNSPSC :

  12352100

• Target :

  DNA/RNA Synthesis; Reference Standards

• Related Pathways :

  Cell Cycle/DNA Damage; Others

• Field of Research :

  Cancer

• Smiles :

  OCC(C)(NCC1=C2C=CC=CC2=C3C(C4=CC=CC=C4C=C3)=C1)CO

• Molecular Formula :

  C23H23NO2

• Molecular Weight :

  345.43

• References & Citations :

  [1]Adams DJ. In vitro pharmacodynamic assay for cancer drug development: application to crisnatol, a new DNA intercalator. Cancer Res. 1989 Dec 1;49 (23) :6615-20. |[2]Patel DK, et al. Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites. Biochem Pharmacol. 1991 Jul 5;42 (2) :337-46. |[3]Patel DK, et al. Disposition, metabolism, and excretion of the anticancer agent crisnatol in the rat. Drug Metab Dispos. 1991 Mar-Apr;19 (2) :491-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards