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Crisnatol

CAT: 0804-HY-108999A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-108999A-01Size:5 mg
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Description
Crisnatol (BWA770U) is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts[1][2][3].
CAS Number
96389-68-3
Product Name Alternative
BWA770U
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/crisnatol.html
Purity
99.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCC(C)(NCC1=C2C=CC=CC2=C3C(C4=CC=CC=C4C=C3)=C1)CO
Molecular Formula
C23H23NO2
Molecular Weight
345.43
References & Citations
[1]Adams DJ. In vitro pharmacodynamic assay for cancer drug development: application to crisnatol, a new DNA intercalator. Cancer Res. 1989 Dec 1;49 (23) :6615-20. |[2]Patel DK, et al. Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites. Biochem Pharmacol. 1991 Jul 5;42 (2) :337-46. |[3]Patel DK, et al. Disposition, metabolism, and excretion of the anticancer agent crisnatol in the rat. Drug Metab Dispos. 1991 Mar-Apr;19 (2) :491-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
BA4028-1Crisnatol
T27085-01Crisnatol mesylate

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