Morphothiadin (mesylate)

CAT: 0804-HY-108917ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-108917ASize:1 Each
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Description
Morphothiadin (GLS4) mesylate is a potent inhibitor of wild-type and Adefovir (HY-B1826) -resistant HBV replication with an IC50 value of 12 nM[1][2].
CAS Number
[1646361-04-7]
Product Name Alternative
GLS4 (mesylate)
UNSPSC
12352005
Target
HBV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C1=C(CN2CCOCC2)N=C(C3=NC=CS3)NC1C4=CC=C(C=C4Br)F)OCC.O=S(O)(C)=O
Molecular Formula
C22H26BrFN4O6S2
Molecular Weight
605.50
References & Citations
[1]Zhou X, et al. Effects of ketoconazole and rifampicin on the pharmacokinetics of GLS4, a novel anti-hepatitis B virus compound, in dogs. Acta Pharmacol Sin. 2013 Nov;34 (11) :1420-6. |[2]Wu G, et al. Preclinical characterization of GLS4, an inhibitor of hepatitis B virus core particle assembly. Antimicrob Agents Chemother. 2013 Nov;57 (11) :5344-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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T204215-01Morphothiadin mesylate
530586Morphothiadin
A17020-2Morphothiadin 2mg
A17020-25Morphothiadin 25mg
A17020-5Morphothiadin 5mg
A17020-10Morphothiadin 10mg
A17020-50Morphothiadin 50mg
A17020-200Morphothiadin 200mg
A17020-1Morphothiadin 1mg
A17020-100Morphothiadin 100mg

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