9-Phenanthrol (Standard)

• Description:

  9-Phenanthrol (Standard) is the analytical standard of 9-Phenanthrol. This product is intended for research and analytical applications. 9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury[1][2].

• UNSPSC:

  12352100

• Target:

  Reference Standards; TRP Channel

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling; Others

• Field of Research:

  Cardiovascular Disease

• Smiles:

  OC1=CC2=CC=CC=C2C3=CC=CC=C13

• Molecular Formula:

  C14H10O

• Molecular Weight:

  194.23

• References & Citations:

  [1]Wang J, et, al. 9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury. PLoS One. 2013 Jul 25;8 (7) :e70587. |[2]Guinamard R, et al. The TRPM4 channel inhibitor 9-phenanthrol. Br J Pharmacol. 2014 Apr;171 (7) :1600-13.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  484-17-3