Osaterone acetate

CAT: 0804-HY-106614Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-106614Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Osaterone acetate is an orally active steroid anti-androgen agent, mainly used for benign prostatic hyperplasia (BPH) in dogs. Osaterone acetate competitively antagonizes androgen receptor and inhibits 5α-reductase, reducing the concentration of dihydrotestosterone (DHT) while blocking the growth-stimulating effects of testosterone and DHT on prostate cells. Osaterone acetate can rapidly alleviate the symptoms of BPH in dogs without affecting the fertility of breeding dogs[1].
CAS Number
[105149-00-6]
UNSPSC
12352005
Hazard Statement
H302-H361
Target
5 alpha Reductase; Androgen Receptor
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Smiles
CC(O[C@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(C(Cl)=C3)=CC(OC4)=O)C)([H])CC2)([H])CC1)C)C(C)=O)=O
Molecular Formula
C22H27ClO5
Molecular Weight
406.90
Precautions
P264-P270-P280-P330-P405-P501
References & Citations
[1]Niżański W, et al. Comparison of Clinical Effectiveness of Deslorelin Acetate and Osaterone Acetate in Dogs with Benign Prostatic Hyperplasia. Animals (Basel) . 2020 Oct 21;10 (10) :1936.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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