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Picenadol (hydrochloride)

CAT: 0804-HY-106601ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106601ASize:1 Each
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Description
Picenadol (LY-150720) hydrochloride is an opioid mixed agonist-antagonist analgesic. Picenadol hydrochloride is an external racemic mixture, where its d-isomer (LY136596) is a potent μ-opioid receptor agonist, and the l-isomer (LY136595) is a weak μ-receptor competitive antagonist, which can inhibit the agonist effect and reduce the risk of dependence. Picenadol hydrochloride has anticholinergic activity[1][2].
CAS Number
74685-16-8
Product Name Alternative
LY-150720 (hydrochloride)
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
CCC[C@@]1(C2=CC(O)=CC=C2)[C@H](CN(C)CC1)C.Cl
Molecular Formula
C16H26ClNO
Molecular Weight
283.84
References & Citations
[1]Carter RB, et al. Effects of LY150720 (picenadol), a novel mixed-action opioid, on schedule-controlled responding in the squirrel monkey. Pharmacol Biochem Behav. 1984 Nov;21 (5) :779-86.|[2]Zimmerman DM, et al. Picenadol. Drug Alcohol Depend. 1985 Feb;14 (3-4) :381-401.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR

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