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E-5842 (citrate)

CAT: 0804-HY-106153BSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106153BSize:1 Each
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Description
E-5842 citrate is a σ receptor ligand (Ki: 4 nM for σ1 receptor) . E-5842 citrate increases levels of Fos in the medial prefrontal cortex and the nucleus accumbens, without affecting the levels of the protein in the striatum. E-5842 citrate can be used in the research of psychiatric disorders[1].
CAS Number
220120-14-9
UNSPSC
12352005
Target
Sigma Receptor
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
FC1=CC=C(C=C1)C2=CCN(CC2)CCCCN3N=CN=C3.O=C(O)CC(O)(CC(O)=O)C(O)=O
Molecular Formula
C23H29FN4O7
Molecular Weight
492.50
References & Citations
[1]Guitart X, et al. The effect of E-5842, a sigma receptor ligand and potential atypical antipsychotic, on Fos expression in rat forebrain. Eur J Pharmacol. 1998 Dec 18;363 (2-3) :127-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Sigma 1 Receptor

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