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Duazomycin (sodium)

CAT: 0804-HY-105723A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105723A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Duazomycin (Duazomycin A) sodium is a glutamine antagonist. Duazomycin sodium can significantly enhance the effectiveness of 6-Mercaptopurine (6-MP) in experimental allergic encephalomyelitis (EAE) without increasing toxicity[1][2].
CAS Number
2839447-07-1
Product Name Alternative
Duazomycin A (sodium)
UNSPSC
12352211
Target
Glutaminase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Purity
99.11
Solubility
H2O : 50 mg/mL
Smiles
[N-]=[N+]=CC(CC[C@@H](C(O[Na])=O)NC(C)=O)=O
Molecular Formula
C8H10N3NaO4
Molecular Weight
235.17
References & Citations
[1]Vogel C L, et al. Enhanced suppression of experimental allergic encephalomyelitis by combination chemotherapy with duazomycin-A and 6-mercaptopurine[J]. Proceedings of the Society for Experimental Biology and Medicine, 1969, 131 (1) : 251-256.|[2]Rosenberg S, et al. Enhanced Suppression of the Secondary Immune Response by Combination of 6-Mercaptopurine ‘Duazomycin A’[J]. Nature, 1963, 199 (4898) : 1101-1102.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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