CEB-1604

• Description :

  CEB-1604 is an NMDA receptor antagonist. CEB-1604 inhibits NMDA-induced currents in oocytes transfected with NMDA receptor isoforms (NR1/NR2A, NR1/NR2B, NR1/NR2C, NR1/NR2D) with IC50 values ranging from 5 to 12 μM. CEB-1604 abolishes NMDA-dependent epileptiform discharges in rat cortical wedge preparations and reduces the depolarizing effects of NMDA. CEB-1604 can be used in the research field of neurological damage diseases[1].

• UNSPSC :

  12352005

• Target :

  IGluR

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  NCC1(C2=CC(C)=CC=C2)[C@H]3C[C@H](C4)C[C@@H]1C[C@H]4C3

• Molecular Formula :

  C18H25N

• Molecular Weight :

  255.40

• References & Citations :

  [1]Scriabine A, et al. Meeting Reports: Thirty-first Annual Meeting of Society for Neuroscience San Diego, CA November 10–15, 2001. CNS Drug Reviews. 2002, 8 (2) : 193-200

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [287173-08-4]