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Pimonidazole (Standard)

CAT: 0804-HY-105129AR-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-105129AR-01Size:5 mg
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Description
Pimonidazole (Standard) is the analytical standard of Pimonidazole. This product is intended for research and analytical applications. Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor[1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2].
CAS Number
70132-50-2
UNSPSC
12352005
Target
Others; Reference Standards
Related Pathways
Others
Field of Research
Cancer
Smiles
OC(CN1C=CN=C1[N+]([O-])=O)CN2CCCCC2
Molecular Formula
C11H18N4O3
Molecular Weight
254.29
References & Citations
[1]Varia MA, et al. Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. Gynecol Oncol. 1998 Nov;71 (2) :270-7.|[2]Masaki Y, et al. Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent "Pimonidazole" in Hypoxia. PLoS One. 2016 Aug 31;11 (8) :e0161639.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

Pimonidazole

Pimonidazole is a C-nitro compound.

CAS Number70132-50-2
PubChem CID50981
IUPAC Name1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol
Molecular FormulaC11H18N4O3
Molecular Weight254.29
XLogP1
Topological Polar Surface Area87.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count18
Formal Charge0
Complexity278
SMILES
C1CCN(CC1)CC(CN2C=CN=C2[N+](=O)[O-])O
InChI
InChI=1S/C11H18N4O3/c16-10(8-13-5-2-1-3-6-13)9-14-7-4-12-11(14)15(17)18/h4,7,10,16H,1-3,5-6,8-9H2
InChIKey
WVWOOAYQYLJEFD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Pimonidazole
CAS: 70132-50-2
CID: 50981
Formula: C11H18N4O3
MW: 254.29
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight254.29
XLogP31
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass254.13789045
Monoisotopic Mass254.13789045
Topological Polar Surface Area87.1 Ų
Heavy Atom Count18
Formal Charge0
Complexity278
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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