Products for Research Use Only
RegisterLogin

Avitriptan

CAT: 0804-HY-105082Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-105082Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Avitriptan is a 5-HT1B/1D receptor agonist, with pKis of 7.44 (5-HT1B rat), 7.68 (5-HT1B human) and 8.36 (5-HT1D human) . Avitriptan constricts the isolated coronary artery. Avitriptan can be used for migraines[1].
CAS Number
151140-96-4
Product Name Alternative
BMS 180048
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Smiles
O=S(NC)(CC1=CC2=C(NC=C2CCCN3CCN(CC3)C4=C(OC)C=NC=N4)C=C1)=O
Molecular Formula
C22H30N6O3S
Molecular Weight
458.58
References & Citations
[1]Saxena PR, et al. Effects of avitriptan, a new 5-HT 1B/1D receptor agonist, in experimental models predictive of antimigraine activity and coronary side-effect potential. Naunyn Schmiedebergs Arch Pharmacol. 1997 Feb;355 (2) :295-302.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
5-HT1 Receptor

Alternative Products

CatalogName
T206109-01Avitriptan
T30229-01Avitriptan Fumarate
MBS5812798Avitriptan HCl

Popular Products