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Sabeluzole (Standard)

CAT: 0804-HY-105022RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105022RSize:1 Each
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Description
Sabeluzole (Standard) is the analytical standard of Sabeluzole. This product is intended for research and analytical applications. Sabeluzole (R 58735), a benzothiazol derivative, has antiischemic, antiepileptic, and cognitive-enhancing properties. Sabeluzole protects rat hippocampal neurons against NMDA- and glutamate-induced neurotoxicity via preventing tau expression. Sabeluzole enhances memory in rats, and prevents the amnesic effect of Chlordiazepoxide. Sabeluzole can be used fro research of Alzheimer's disease[1][2].
CAS Number
104383-17-7
Product Name Alternative
R 58735 (Standard)
UNSPSC
12352005
Target
Reference Standards; Tau Protein
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
CN(C1CCN(CC(O)COC2=CC=C(F)C=C2)CC1)C3=NC4=C(C=CC=C4)S3
Molecular Formula
C22H26FN3O2S
Molecular Weight
415.52
References & Citations
[1]Hlinák Z, et al. Sabeluzole improves social recognition and antagonizes chlordiazepoxide's effect on habituation in the rat. Psychopharmacology (Berl) . 1991;104 (4) :505-9. |[2]Uberti D, et al. Priming of cultured neurons with sabeluzole results in long-lasting inhibition of neurotoxin-induced tau expression and cell death. Synapse. 1997 Jun;26 (2) :95-103.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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