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Balapiravir (Standard)

CAT: 0804-HY-10443RSize: 1 EachDry Ice: NoHazardous: No
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Description
Balapiravir (Standard) is the analytical standard of Balapiravir. This product is intended for research and analytical applications. Balapiravir (Ro 4588161; R1626) is an orally active proagent of a nucleoside analogue inhibitor of the RNA-dependent RNA polymerase (RdRp) of HCV (R1479; 4'-Azidocytidine) . Balapiravir has anti-HCV activity[1][2][3]. Balapiravir is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
CAS Number
690270-29-2
Product Name Alternative
Ro 4588161 (Standard) ; R1626 (Standard)
UNSPSC
12352005
Target
DNA/RNA Synthesis; HCV; Reference Standards
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Others
Field of Research
Infection
Smiles
O=C1N=C(N)C=CN1[C@@H]2O[C@](N=[N+]=[N-])(COC(C(C)C)=O)[C@@H](OC(C(C)C)=O)[C@H]2OC(C(C)C)=O
Molecular Formula
C21H30N6O8
Molecular Weight
494.50
References & Citations
[1]Nguyen NM, et al. A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients. J Infect Dis. 2013 May 1;207 (9) :1442-1450.|[2]Nelson DR, et al. Balapiravir plus peginterferon alfa-2a (40KD) /ribavirin in a randomized trial of hepatitis C genotype 1 patients.Ann Hepatol. 2012 Jan-Feb;11 (1) :15-31.|[3]Yen-Liang Chen, et al. Activation of Peripheral Blood Mononuclear Cells by Dengue Virus Infection Depotentiates Balapiravir. J Virol. 2014 Feb;88 (3) :1740-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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A11335-25Balapiravir 25mg
A11335-10Balapiravir 10mg
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