PIT-1 (Standard)

CAT: 0804-HY-103224RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-103224RSize:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PIT-1 (Standard) is the analytical standard of PIT-1. This product is intended for research and analytical applications. PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo[1].
CAS Number
[53501-41-0]
UNSPSC
12352005
Target
PI3K; Reference Standards
Related Pathways
Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(NC(NC1=CC([N+]([O-])=O)=CC(Cl)=C1O)=S)C2=CC=CC=C2
Molecular Formula
C14H10ClN3O4S
Molecular Weight
351.76
References & Citations
[1]Miao B, et al. Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains. Proc Natl Acad Sci U S A. 2010 Nov 16;107 (46) :20126-31.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-103224-01PIT-1
HY-124348-01DM-PIT-1
HY-108662-01PIT
HY-34444R1,1-Dioxothiolan (Standard)
HY-Y1004R-011-Decanol (Standard)
HY-Y0289R-011-Dodecanol (Standard)
HY-W127493R1-Hexacosanol (Standard)
HY-W032022R-011-Hexanol (Standard)
HY-N2579R-011-Kestose (Standard)
HY-15701R-01Leukadherin-1 (Standard)

Alternative Products

CatalogName
350336Peptide Standard 1
OR1101406-011,1,1,2-Tetrachloroethane Standard
WINE-1Organic Wine Standard 1
92654-1Standard Nutrient Agar No.1
DM 2224Standard Nutrient Broth No. 1
92654-01Standard Nutrient Agar No.1
DM 2210Standard Nutrient Agar No. 1
C160-50ULEndothelin-1 Standard, 50UL
548-ISInternal Standard Endosulfan-1 - 1ML
MBS483007-01PGHS-1 Standard, Native Ovine

Popular Products