Products for Research Use Only

Mericitabine (Standard)

CAT: 0804-HY-10240R-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10240R-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mericitabine (Standard) is the analytical standard of Mericitabine. This product is intended for research and analytical applications. Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.
CAS Number
940908-79-2
Product Name Alternative
RG 7128 (Standard) ; R-7128 (Standard) ; PSI 6130 diisobutyrate (Standard)
UNSPSC
12352005
Target
HCV; Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
O=C1N=C(C=CN1[C@@H]([C@@](C)([C@@H]2OC(C(C)C)=O)F)O[C@@H]2COC(C(C)C)=O)N
Molecular Formula
C18H26FN3O6
Molecular Weight
399.41
References & Citations
[1]Le Pogam S, et al. Characterization of HCV quasispecies dynamics upon short term dual-therapy with the HCV NS5B nucleoside polymerase inhibitor mericitabine and the NS3/4 protease inhibitor danoprevir. Antimicrob Agents Chemother. 2012 Nov;56 (11) :5494-5|[2]Soriano V, et al. Directly acting antivirals against hepatitis C virus. J Antimicrob Chemother. 2011 Aug;66 (8) :1673-86|[3]Guedj J, et al. Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128) . Hepatology. 2012 Apr;55 (4) :1030-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards