BEPP (hydrochloride)

• Description :

  BEPP hydrochloride is a double-stranded RNA-dependent protein kinase (PKR) inducer and antiviral agent. BEPP hydrochloride effectively inhibits the growth of human lung cancer cell lines overexpressing PKR and induces apoptosis and activates caspase-3 in sensitive cells. In addition, BEPP hydrochloride can also significantly inhibit vaccinia virus replication[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Caspase

• Related Pathways :

  Apoptosis

• Field of Research :

  Cancer; Infection

• Purity :

  96.94

• Solubility :

  DMSO : 4.17 mg/mL (ultrasonic)

• Smiles :

  OC(COC1=CC=CC=C1)CN2C3=CC=CC=C3N(CC4=CC=CC=C4)C2=N.Cl

• Molecular Formula :

  C23H24ClN3O2

• Molecular Weight :

  409.91

• References & Citations :

  [1]Hu W, et al. Double-stranded RNA-dependent protein kinase-dependent apoptosis induction by a novel small compound. J Pharmacol Exp Ther. 2009 Mar;328 (3) :866-72.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [455311-98-5]