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HCH6-1 (Standard)

CAT: 0804-HY-101283RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101283RSize:1 Each
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Description
HCH6-1 (Standard) is the analytical standard of HCH6-1. This product is intended for research and analytical applications. HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases[1].
CAS Number
1435265-06-7
Target
Formyl Peptide Receptor (FPR) ; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Inflammation/Immunology
Smiles
O=C(N[C@H](C(N[C@@H](C(OC)=O)CC1=CC=CC=C1)=O)CC2=CNC3=C2C=CC=C3)C4=CC=CC=C4
Molecular Formula
C28H27N3O4
Molecular Weight
469.53
References & Citations
[1]Yang SC, et al. Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1. Free Radic Biol Med. 2017 May;106:254-269
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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