Products for Research Use Only
RegisterLogin

SNC80 (Standard)

CAT: 0804-HY-101202RSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101202RSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SNC80 (Standard) is the analytical standard of SNC80. This product is intended for research and analytical applications. SNC80 (NIH 10815) is a potent, highly selective and non-peptide δ-opioid receptor agonist with a Ki of 1.78 nM and an IC50 of 2.73 nM. SNC80 also selectively activates μ-δ heteromer in HEK293 cells with an EC50 of 52.8 nM. SNC80 shows antinociceptive, antihyperalgesic and antidepressant‐like effects. SNC80 has the potential for multiple headache disorders treatment[1][2][3][4][5][6].
CAS Number
156727-74-1
Target
Opioid Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(N(CC)CC)C1=CC=C([C@@H](N2[C@@H](C)CN(CC=C)[C@H](C)C2)C3=CC=CC(OC)=C3)C=C1
Molecular Formula
C28H39N3O2
Molecular Weight
449.63
References & Citations
[1]Moye LS, et al. Delta opioid receptor agonists are effective for multiple types of headache disorders. Neuropharmacology. 2019 Apr;148:77-86.|[2]Bilsky EJ, et al. SNC 80, a selective, nonpeptidic and systemically active opioid delta agonist. J Pharmacol Exp Ther. 1995 Apr;273 (1) :359-66.|[3]Calderon SN, et al. Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+) -4-[ (alpha R) -alpha- ((2S,5R) -4-allyl-2,5-dimethyl-1-piperazinyl) -3- methoxybenzyl]-N, N-diethylbenzamide (SNC 80) : a highly selective, nonpeptide delta opioid receptor agonist. J Med Chem. 1994 Jul 8;37 (14) :2125-8.|[4]Vicente-Sanchez A, et al. The delta opioid receptor tool box. Neuroscience. 2016 Dec 3;338:145-159.|[5]Dripps IJ, et al. Role of signalling molecules in behaviours mediated by the δ opioid receptor agonist SNC80. Br J Pharmacol. 2018 Mar;175 (6) :891-901.|[6]Metcalf MD, et al. The δ opioid receptor agonist SNC80 selectively activates heteromeric μ-δ opioid receptors. ACS Chem Neurosci. 2012 Jul 18;3 (7) :505-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-101202-01SNC80
HY-101202A-01(Rac) -SNC80
HY-P2274RArgifin (Standard)
HY-N9362REmodinanthrone (Standard)
HY-N7948RIsomaltotetraose (Standard)
HY-N7640RDeoxylimonin (Standard)
HY-N7617RToralactone (Standard)
HY-N7541RAntrodin A (Standard)
HY-N6739RBeauvericin (Standard)
HY-N6687RCalcimycin (Standard)

Alternative Products

CatalogName
GK2247-25mgSNC80
MBS5815730(Rac)-SNC80
217799SNC80 (Delta Opioid Receptor Agonist, SNC80)
T73631-01(Rac) -SNC80
045306-01SNC80 ((+) -4-N, N-diethylbenzamide)
MBS6023668-01SNC80 ((+)-4-N,N-diethylbenzamide)
abx098968-01Standard
ST-08004-02Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard + BRS Electrolyte
RE21029ARAb Standard A (Standard 0) 20 ml
ST-80004-01Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard for biological samples

Popular Products