KI696 (Standard)

• Description :

  KI696 (Standard) is the analytical standard of KI696 (HY-101140) . This product is intended for research and analytical applications. KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction[1].

• Target :

  Keap1-Nrf2; Reference Standards

• Related Pathways :

  NF-κB; Others

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Smiles :

  COC1=C(N2C)C(N=N2)=CC([C@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1

• Molecular Formula :

  C28H30N4O6S

• Molecular Weight :

  550.63

• References & Citations :

  [1]Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59 (8) :3991-4006.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [1799974-70-1]