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KI696 (Standard)

CAT: 0804-HY-101140RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101140RSize:1 Each
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Description
KI696 (Standard) is the analytical standard of KI696. This product is intended for research and analytical applications. KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction[1].
CAS Number
1799974-70-1
Target
Keap1-Nrf2; Reference Standards
Related Pathways
NF-κB; Others
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
COC1=C(N2C)C(N=N2)=CC([C@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1
Molecular Formula
C28H30N4O6S
Molecular Weight
550.63
References & Citations
[1]Davies TG, et al. Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery. J Med Chem. 2016 Apr 28;59 (8) :3991-4006.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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