Temocapril (Standard)

• Description:

  Temocapril (Standard) is the analytical standard of Temocapril. This product is intended for research and analytical applications. Temocapril is an orally active angiotensin-converting enzyme (ACE) inhibitor. Temocapril can be used for the research of hypertension, congestive heart failure, acute myocardial infarction, insulin resistance, and renal diseases[1][2].

• UNSPSC:

  12352005

• Target:

  Angiotensin-converting Enzyme (ACE) ; Reference Standards

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=C (O) CN1C[C@@H] (C2=CC=CS2) SC[C@H] (N[C@H] (C (OCC) =O) CCC3=CC=CC=C3) C1=O

• Molecular Formula:

  C23H28N2O5S2

• Molecular Weight:

  476.61

• References & Citations:

  [1]Fukami T, et al. In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities. Drug Metab Dispos. 2010 Dec;38 (12) :2173-8.|[2]Kawasaki H, et al. Angiotensin inhibits neurotransmission of calcitonin gene-related peptide-containing vasodilator nerves in mesenteric artery of spontaneously hypertensive rats. J Pharmacol Exp Ther. 1998 Feb;284 (2) :508-15. |[3]Yuan Z, et al. Temocapril treatment ameliorates autoimmune myocarditis associated with enhanced cardiomyocyte thioredoxin expression. Cardiovasc Res. 2002 Aug 1;55 (2) :320-8.|[4]Ohnishi K, et al. Angiotensin-converting enzyme inhibitor does not suppress renal angiotensin II levels in angiotensin I-infused rats. J Pharmacol Sci. 2013;122 (2) :103-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  111902-57-9