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RPR121056 (Standard)

CAT: 0804-HY-100620R-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100620R-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RPR121056 (Standard) is the analytical standard of RPR121056. This product is intended for research and analytical applications. RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1].
CAS Number
181467-56-1
Product Name Alternative
APC (Standard)
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Drug Metabolite; Reference Standards; Topoisomerase
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Cancer
Smiles
O=C(N1CCC(NCCCCC(O)=O)CC1)OC2=CC=C3N=C4C(CN5C(C(COC([C@@]6(CC)O)=O)=C6C=C54)=O)=C(CC)C3=C2
Molecular Formula
C33H38N4O8
Molecular Weight
618.68
References & Citations
[1]Alvau MD, et al. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan. Anal Chem. 2018 May 15;90 (10) :6012-6019.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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