DTP3 (Standard)

CAT: 0804-HY-100538RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-100538RSize:1 Each
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Description
DTP3 (Standard) is the analytical standard of DTP3 (HY-100538) . This product is intended for research and analytical applications. DTP3 TFA is a potent and selective GADD45β/MKK7 inhibitor. DTP3 TFA targets an essential, cancer-selective cell-survival module downstream of the NF-κB pathway[1].
CAS Number
[1809784-29-9]
Target
DNA/RNA Synthesis; JAK; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; JAK/STAT Signaling; Others; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Cancer
Smiles
O=C(N[C@H](CC1=CC=CC=C1)C(N)=O)[C@H](NC([C@H](NC(C)=O)CC2=CC=C(O)C=C2)=O)CCCNC(N)=N
Molecular Formula
C26H35N7O5
Molecular Weight
525.60
References & Citations
[1]Tornatore L, et al. Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7inhibitor and clinical candidate, DTP3. Toxicol Rep. 2019 Apr 19;6:369-379.|[2]Tornatore L, et al. Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors. Cancer Cell. 2014 Oct 13;26 (4) :495-508.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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