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CCF642 (Standard)

CAT: 0804-HY-100430RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-100430RSize:1 Each
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Description
CCF642 (Standard) is the analytical standard of CCF642. This product is intended for research and analytical applications. CCF642 is a potent protein disulfide isomerases (PDI) inhibitor with an IC50 of 2.9 μM. CCF642 causes acute endoplasmic reticulum (ER) stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. CCF642 has broad anti-multiple myeloma activity[1].
CAS Number
346640-08-2
Target
Apoptosis; PDI; Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C1N(C2=CC=C(OC)C=C2)C(S/C1=C/C3=CC=C([N+]([O-])=O)S3)=S
Molecular Formula
C15H10N2O4S3
Molecular Weight
378.45
References & Citations
[1]Vatolin S et al. Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma. Cancer Res. 2016 Jun 1;76 (11) :3340-50.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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B8353-25CCF642
A16122-500CCF642 500mg
A16122-100CCF642 100mg
A16122-50CCF642 50mg
A16122-25CCF642 25mg
A16122-10CCF642 10mg
A16122-2CCF642 2mg
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