MS049 (Standard)

CAT: 0804-HY-100360RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-100360RSize:1 Each
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Description
MS049 (Standard) is the analytical standard of MS049 (HY-100360) . This product is intended for research and analytical applications. MS049, a chemical probe, is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. MS049 reduces levels of Med12me2a and H3R2me2a in HEK293 cells. MS049 is not toxic and does not affect the growth of HEK293 cells[1].
CAS Number
[1502816-23-0]
Target
Histone Methyltransferase; Reference Standards
Related Pathways
Epigenetics; Others
Field of Research
Cancer
Smiles
CNCCN1CCC(OCC2=CC=CC=C2)CC1
Molecular Formula
C15H24N2O
Molecular Weight
248.36
References & Citations
[1]Shen Y et al. Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6. J Med Chem. 2016 Sep 15.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
MF-0093944-01MS049
M19404-01MS049 2HCl
C3776-10MS049 (hydrochloride)
A12160-50MS049 50mg
A12160-10MS049 10mg
A12160-200MS049 200mg
MF-0043083-01MS049 dihydrochloride
A12160-100MS049 100mg
A12160-25MS049 25mg

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