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BAPTA (tetrasodium)

CAT: 0804-HY-100168A-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100168A-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][3].
CAS Number
[126824-24-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Phospholipase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
99.70
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O[Na])CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O[Na])=O)CC(O[Na])=O)CC(O[Na])=O
Molecular Formula
C22H20N2Na4O10
Molecular Weight
564.36
Precautions
H302, H315, H319, H335
References & Citations
[1]R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19 (11) :2396-404. |[2]Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis (2-aminophenoxy) ethane N, N, N', N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38 (6) :547-56. |[3]M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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