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Tubercidin (Standard)

CAT: 0804-HY-100126R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100126R-01Size:5 mg
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Description
Tubercidin (Standard) is the analytical standard of Tubercidin. This product is intended for research and analytical applications. Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC50 of 0.02 μM[1]. Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis[2]. Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP[1]. Tubercidin has antiviral activity[2].
CAS Number
69-33-0
Product Name Alternative
7-Deazaadenosine (Standard)
UNSPSC
12352005
Target
Antibiotic; Bacterial; DNA/RNA Synthesis; Influenza Virus; Reference Standards
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Others
Field of Research
Infection
Smiles
O[C@H]1[C@@H](O)[C@H](N2C=CC3=C2N=CN=C3N)O[C@@H]1CO
Molecular Formula
C11H14N4O4
Molecular Weight
266.26
References & Citations
[1]Bloch A, et al. On the mode of action of 7-deaza-adenosine (Tubercidin) . Biochim Biophys Acta. 1967 Mar 29;138 (1) :10-25.|[2]Kouni MH, et al. Prevention of tubercidin host toxicity by nitrobenzylthioinosine 5'-monophosphate for the treatment of schistosomiasis. Antimicrob Agents Chemother. 1989 Jun;33 (6) :824-7.|[3]Bergstrom DE, et al. Antiviral activity of C-5 substituted tubercidin analogues. J Med Chem. 1984 Mar;27 (3) :285-92.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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