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Rabbit Polyclonal Antibody to EIF2S1

CAT: 1725-P13304-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P13304-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]) .
Product Name Alternative
EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha
Swiss Prot
P05198
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human EIF2S1
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
EIF2S1
Bands Size
36 kDa

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