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Rabbit Polyclonal Antibody to EEA1

CAT: 1725-P13294-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P13294-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EEA1 is an early endosomal marker and a Rab5 effector protein essential for early endosomal membrane fusion and trafficking. The carboxy terminus of EEA1 contains a FYVE domain which binds to phosphatidylinositol-3-phosphate (PtdIns (3) P), targeting EEA1 to early endosomes. The stable association of EEA1 with the endosomal membrane is regulated by PI3 kinase, Rab5 and calcium/calmodulin. Once on the membrane, EEA1 interacts with Rab5, NSF and syntaxin 13 to promote early endosomal membrane docking and fusion.
Product Name Alternative
MST105; ZFYVE2; MSTP105
Swiss Prot
Q15075
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human EEA1
Clonality
Polyclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
EEA1
Bands Size
163 kDa