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Rabbit Polyclonal Antibody to YTHDF1

CAT: 1725-P12864-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P12864-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. Specifically recognizes and binds N6-methyladenosine (m6A) -containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451) . M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625) . Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440) .
Product Name Alternative
C20orf21
Swiss Prot
Q9BYJ9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human YTHDF1
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
YTHDF1

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