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Rabbit Polyclonal Antibody to CASP4

CAT: 1725-P12853-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P12853-01Size:50 µL
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Description
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Product Name Alternative
TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE (rel) II
Swiss Prot
P49662
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human CASP4
Clonality
Polyclonal
Applications
IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CASP4

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