Rabbit Polyclonal Antibody to NCKAP1

CAT: 1725-P11968-01Size: 50 µLDry Ice: NoHazardous: No

1 / 1

CAT#:1725-P11968-01Size:50 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD) -affected brains, suggesting a possible role in the disease.

Product Name Alternative

HEM2; NAP1; NAP125; p125Nap1

Swiss Prot

Q9Y2A7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide of human NCKAP1

Clonality

Polyclonal

Applications

IHC

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Formulation

Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Antibody Type

Primary antibody

Protein Name

NCKAP1

Rabbit Polyclonal Antibody to NCKAP1

Popular Products