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Rabbit Polyclonal Antibody to RNF126

CAT: 1725-P11106-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P11106-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. RNF126 interacts with p21 and RNF126 over-expression increased p21 protein ubiquitination in an E3 ligase activity-dependent manner. RNF126 knockdown induced loss of cell viability in MDA-MB-231 and PC-3 can be partially rescued by depletion of p21. RNF126 stable knockdown in PC3 inhibited tumor growth in SCID mice.
Swiss Prot
Q9BV68
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human RNF126
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
RNF126
Bands Size
38 kDa

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