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Rabbit Polyclonal Antibody to ACVR2A

CAT: 1725-P10705-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P10705-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Product Name Alternative
ACVR2, ACTRII
Swiss Prot
P27037
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human ACVR2A
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
ACVR2A
Bands Size
58 kDa

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